7 IBDM teams have received grants from the Agence Nationale pour la Recherche (ANR) in 2021. Congratulations to Vincent Bertrand, Harold Cremer, Pascale Durbec, André Le Bivic, Pierre-François Lenne, Cédric Maurange and Julien Royet.

Jules Lavalou and Qiyan Mao from Thomas Lecuit’s team report that Toll-8 controls myosin-II planar polarity in Drosophila embryos and wing discs via a physical interaction with the GPCR Cirl/latrophilin.

Antoine Barrière and Amel Toudji-Zouaz in the Bertrand team developed a new method to image and quantify transcription in vivo.

This study published in Cell Death & Disease, conducted by the team of L. Kerkerian-Le Goff provides the first evidence for a role of the stress-induced protein TP53INP1 in the maintenance of neuronal homeostasis in ageing and Parkinson’s disease-related stress conditions.

Tafalgie Therapeutics is a new start-up company created in November 2020, based on the work of Aziz Moqrich’s team “Chronic pain: cellular and molecular mechanisms” at IBDM.

By combining genetics in the fruit fly Drosophila with state-of-the-art imaging and deep-learning, researchers at IBDM have found that mitochondria coordinate their formation with myofibril development to match the correct muscle type.

Alexandre CHUYEN, who did his doctoral thesis under the supervision of Andrea Pasini in the Kodjabachian team, was awarded the 2021 Thesis Prize from the SFBD.

A study published in Developmental Cell by the Kodjabachian team reveals how multiciliated cells are distributed at regular intervals in the Xenopus embryonic epidermis.

The team of Yacine Graba and Andrew Saurin identified an atypical function for HoxB genes during spinal cord development.

The team of Alphée Michelot, in collaboration with the team of Pekka Lappalainen (University of Helsinki) identified and characterized a family of highly sensitive fluorescent nucleotide analogues structurally compatible with actin.