We invite applications from creative early-career scientists investigating a fundamental question in developmental biology to join the IBDM community.

Our findings provide mechanistic insight into the mechanism by which TAFA4 reverses injury-induced mechanical hypersensitivity, by restoring normal spinal neuron activity, and highlight the considerable potential of TAFA4 as a treatment for injury-induced mechanical pain.

Through an international collaboration, using breast cancer as a biological paradigm, Flavio Maina Team publishes a work in the Theranostics journal exemplifying how specificity in targeting cell cycle regulators is essential for combinatorial cancer therapies.

Lydia Kerkerian-Le Goff was awarded the Chevalier de la Légion d’Honneur by Geneviève Rougon on Friday 1 October at the Hexagon, Emeritus researcher at the Institute of Neurosciences at La Timone…

Americans David Julius, born in 1955 in New York, and Ardem Patapoutian, born in 1967 in Beirut and of Lebanese-Armenian origin, were awarded the prize for their discoveries of temperature and touch receptors.

7 IBDM teams have received grants from the Agence Nationale pour la Recherche (ANR) in 2021. Congratulations to Vincent Bertrand, Harold Cremer, Pascale Durbec, André Le Bivic, Pierre-François Lenne, Cédric Maurange and Julien Royet.

Jules Lavalou and Qiyan Mao from Thomas Lecuit’s team report that Toll-8 controls myosin-II planar polarity in Drosophila embryos and wing discs via a physical interaction with the GPCR Cirl/latrophilin.

Antoine Barrière and Amel Toudji-Zouaz in the Bertrand team developed a new method to image and quantify transcription in vivo.

This study published in Cell Death & Disease, conducted by the team of L. Kerkerian-Le Goff provides the first evidence for a role of the stress-induced protein TP53INP1 in the maintenance of neuronal homeostasis in ageing and Parkinson’s disease-related stress conditions.

Tafalgie Therapeutics is a new start-up company created in November 2020, based on the work of Aziz Moqrich’s team “Chronic pain: cellular and molecular mechanisms” at IBDM.