The team of Alphée Michelot, in collaboration with the team of Pekka Lappalainen (University of Helsinki) identified and characterized a family of highly sensitive fluorescent nucleotide analogues structurally compatible with actin.

Read more...

The teams of F Maina and L Kerkerian-Le Goff publish in Stem Cells Translational Medicine a work led by Rosanna Dono showing that levels of the signal modulator GLYPICAN-4 are critical for the generation of midbrain dopamine neurons from human induced pluripotent stem cells and for overcoming their tumorigenic properties.

Read more...

Maina Team publishes in Advanced Science the setup of a genetic system that models, in mice, the heterogeneity and primary resistance to treatment of human Triple Negative Breast Cancer (TNBC).

Read more...

A publication from the Prud’homme team shows how the sexually dimorphic expression pattern of an X-linked gene is controlled by an interallelic interaction, a phenomenon known as transvection.

Read more...

Schnorrer team and colleagues discovered that a signalling pathway, called the Hippo pathway, is controlling muscle growth during development of Drosophila flight muscles.

Read more...

Maina Team publishes in Journal of Hepatology. The team found that ADAMTSL5 is an epigenetically activated oncogene overexpressed in a large fraction of human HCC patients and in HCC mouse models.

Read more...

Benoit Aigouy, from the Prud’homme team, developed EPySeg, an open-source software that uses deep learning to segment membrane-stained epithelial tissues, from any organism, automatically and very efficiently.

Read more...

A publication from the Prud’homme team, in collaboration with the group of N. Gompel explores how the spatial pattern and quantitative regulatory information is encoded in the enhancer sequence of a developmental gene.

Read more...

A publication from the Kelly team in Nature Communications, conducted by Caroline Choquet and Lucile Miquerol, focuses on the development of cardiac Purkinje fibers that serve as electrical cables in the ventricles to synchronize heartbeats.

Read more...

In a paper published in elife, Nathalie Coré from the Cremer team describes a new regulatory cascade, implicating transcription factors and a microRNA, that controls how neural stem cells determine which type of neuron they produce.

Read more...