7 IBDM teams have received grants from the Agence Nationale pour la Recherche (ANR) in 2021. Congratulations to Vincent Bertrand, Harold Cremer, Pascale Durbec, André Le Bivic, Pierre-François Lenne, Cédric Maurange and Julien Royet.

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Jules Lavalou and Qiyan Mao from Thomas Lecuit’s team report that Toll-8 controls myosin-II planar polarity in Drosophila embryos and wing discs via a physical interaction with the GPCR Cirl/latrophilin.

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Antoine Barrière and Amel Toudji-Zouaz in the Bertrand team developed a new method to image and quantify transcription in vivo.

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This study published in Cell Death & Disease, conducted by the team of L. Kerkerian-Le Goff provides the first evidence for a role of the stress-induced protein TP53INP1 in the maintenance of neuronal homeostasis in ageing and Parkinson’s disease-related stress conditions.

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Tafalgie Therapeutics is a new start-up company created in November 2020, based on the work of Aziz Moqrich’s team “Chronic pain: cellular and molecular mechanisms” at IBDM.

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By combining genetics in the fruit fly Drosophila with state-of-the-art imaging and deep-learning, researchers at IBDM have found that mitochondria coordinate their formation with myofibril development to match the correct muscle type.

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Alexandre CHUYEN, who did his doctoral thesis under the supervision of Andrea Pasini in the Kodjabachian team, was awarded the 2021 Thesis Prize from the SFBD.

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A study published in Developmental Cell by the Kodjabachian team reveals how multiciliated cells are distributed at regular intervals in the Xenopus embryonic epidermis.

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The team of Yacine Graba and Andrew Saurin identified an atypical function for HoxB genes during spinal cord development.

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The team of Alphée Michelot, in collaboration with the team of Pekka Lappalainen (University of Helsinki) identified and characterized a family of highly sensitive fluorescent nucleotide analogues structurally compatible with actin.

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